The long run of success Endrass had seen both as 1WO of U-47 and skipper of U-46 was then to come to a sudden end. On his first patrol as commander of U-567, he ran into trouble north-east of the Azores in the shape of the British attack vessel HMS Deptford. Succumbing to the Deptford's depth charge attack, U-567 went down with all hands on 21 December 1941.