Wuhan virus 2020

[Jimbuna]

[Jimbuna]

President Trump rejects mandatory masks: "I want people to have a certain freedom"

Top US infectious diseases expert Dr Anthony Fauci says everyone should use them.

UN Secretary General António Guterres has criticised the world’s biggest powers for failing to work together to tackle the pandemic.

PM Boris Johnson gives English councils new powers to manage local outbreaks.

Indian actress Aishwarya Rai Bachchan is taken to hospital after testing positive for Covid-19

Iran's president says 25 million Iranians have already been infected by Covid-19

4 million people in Barcelona in north-east Spain are urged to stay at home for 15 days.

Globally there have been 14.1 million cases since the outbreak began, with 602,657 deaths.

[Jimbuna]

Councils in England have new powers to close shops, cancel events and shut outdoor public spaces in order to manage local outbreaks of the virus.

Health Secretary Matt Hancock has called for an urgent review into covid death data in England after Public Health England confirmed reported deaths may have included people months before they died.

EU leaders discuss compromise on Covid recovery deal.

The opening of parliament in Australia has been delayed by several weeks due to the spread of the virus in the country’s two most populous states.

The US has now recorded more than 3.6 million cases of the virus and more than 139,000 people have died.

[Jimbuna]

[Jimbuna]

[Skybird]

https://edition.cnn.com/2020/07/19/h...ntl/index.html

Meanwhile, health authorities in the UK and Italy, two of the European nations worst hit by the coronavirus pandemic, are starting to offer rehabilitation services to Covid-19 survivors.
These will likely need to be wide-ranging, since research now indicates that coronavirus is a multi-system disease that can damage not only the lungs, but the kidneys, liver, heart, brain and nervous system, skin and gastrointestinal tract.
Dr Piero Clavario, director of the post-Covid rehab institute attended by Pescarolo in Genoa, said his team had started contacting several hundred Covid-survivors treated by hospitals in the district in May. Of those, they have now visited more than 50.
"They are not only those that were in ICU and intubated because of Covid, but also patients that spent not more than three days in the hospitals and then went home," he said. "We investigate aspects that escape standard virological and pulmonary exams."

Skin...? I missed that.

[Jimbuna]

More than 600,000 people have died with the coronavirus around the world
Nearly a quarter of them were in the US.

The world has seen the largest single-day increase in cases, the WHO says.

The number of new cases of coronavirus rose by almost 260,000 in 24 hours.

The EU is in its third day of talks to try to agree a rescue package for virus-hit countries.

Millions of people have been told to stay at home amid an outbreak in the Spanish region of Catalonia.

The global number of infections now stands at 14.3 million - Johns Hopkins University.

[Jimbuna]

The number of people who have died from coronavirus in England may have been overstated by up to 4,000

The Australian city of Melbourne is set to make mask wearing in public mandatory as it faces a spike in cases.

The number of active cases of coronavirus in the Czech Republic has risen to 4,764, more than the previous high of 4,737 in April.

Russia’s ambassador to the UK has rejected allegations that his country’s intelligence services tried to steal coronavirus vaccine research.

Iran has confirmed 209 deaths and 2,182 confirmed cases in the past 24 hours.
Of the new people diagnosed, 1,324 have been hospitalised, a health ministry spokeswoman said.

Hong Kong Chief Executive Carrie Lam has now announced that the city will conduct 10,000 tests a day. She also announced that authorities would make wearing face masks mandatory in indoor public spaces.

Beijing will lower its coronavirus emergency response level from three to two, an official said on Sunday.
The Chinese capital has reported no new cases over the past 13 days.

[Jimbuna]

[mapuc]

Something must be missing in this case

Most strangely, all of the crew tested negative and self-isolated for two weeks before boarding the ship. This, in theory, would mean the chances of Covid-19 being introduced to the ship and its crew were slim-to-none.

https://www.iflscience.com/health-an...ps-scientists/

Markus

[Skybird]

On deep-frozen food the virus can survive around one year, I recently red. Virusses outside a physiological ambience (animal body) usually like it

- moist or even wet (not dry)
- dark (no UV)
- cold (not too warm or even hot).

Household fridges are usually around -28°C.

Just an idea.


^This is why virusses usually quickly become ineffective in the open nature outside caves: in woods, lakes, on plants and trees. Eitherwrong humidity level, UV or warong temperature will deactivate them quickly. Chemical and bacteriological agents you have to look out for, virusses are low on your list if you go camping or trekking and ask yourself whether you can use this or that water you find. Virusses in free nature will meet you most likely in form of infested animals and insects. Smear infection from stones, rocks, plants, leaves, grass, trees however is practically non-existent.

[Skybird]

https://pubmed.ncbi.nlm.nih.gov/32252338/


This article reviews the roles of vitamin D in reducing the risk of respiratory tract infections, knowledge about the epidemiology of influenza and COVID-19, and how vitamin D supplementation might be a useful measure to reduce risk. Through several mechanisms, vitamin D can reduce risk of infections. Those mechanisms include inducing cathelicidins and defensins that can lower viral replication rates and reducing concentrations of pro-inflammatory cytokines that produce the inflammation that injures the lining of the lungs, leading to pneumonia, as well as increasing concentrations of anti-inflammatory cytokines. Several observational studies and clinical trials reported that vitamin D supplementation reduced the risk of influenza, whereas others did not. Evidence supporting the role of vitamin D in reducing risk of COVID-19 includes that the outbreak occurred in winter, a time when 25-hydroxyvitamin D (25(OH)D) concentrations are lowest; that the number of cases in the Southern Hemisphere near the end of summer are low; that vitamin D deficiency has been found to contribute to acute respiratory distress syndrome; and that case-fatality rates increase with age and with chronic disease comorbidity, both of which are associated with lower 25(OH)D concentration. To reduce the risk of infection, it is recommended that people at risk of influenza and/or COVID-19 consider taking 10,000 IU/d of vitamin D3 for a few weeks to rapidly raise 25(OH)D concentrations, followed by 5000 IU/d. The goal should be to raise 25(OH)D concentrations above 40-60 ng/mL (100-150 nmol/L). For treatment of people who become infected with COVID-19, higher vitamin D3 doses might be useful. Randomized controlled trials and large population studies should be conducted to evaluate these recommendations.

[Skybird]

https://www.medrxiv.org/content/10.1....01.20079376v2


Through its immunological functions, vitamin D attenuates inflammatory responses to respiratory viruses. Vitamin D deficiency might be a highly prevalent risk factor for severe SARS-CoV-2 infections. Objective. To investigate the level of vitamin D deficiency in West Flanders, Belgium and its correlation to severity of COVID-19 as staged by CT Design. Retrospective observational study Setting. Central network hospital Participants. 186 SARS-CoV-2-infected patients hospitalized from March 1, 2020 to April 7, 2020 Main outcome measure. Analysis of 25(OH)D in COVID-19 patients versus season/age/sex-matched diseased controls Results. The rate of vitamin D deficiency (25(OH)D<20 ng/mL) in West Flanders varies with age, sex and season but is overall very high (39.9%) based on analysis of 16274 control samples. We measured 25(OH)D levels in 186 COVID-19 patients (109 males (median age 68 years, IQR 53-79) and 77 females (median age 71 years, IQR 65-74)) and 2717 age/season-matched controls (999 males (median age 69 years, IQR 53-81) and 1718 females (median age 68 years, IQR 43-83)). COVID-19 patients showed lower median 25(OH)D (18.6 ng/mL, IQR 12.6-25.3, versus 21.5 ng/mL, IQR 13.9-30.8; P=0.0016) and higher vitamin D deficiency rates (58.6% versus 45.2%, P=0.0005). Surprisingly, this difference was restricted to male COVID-19 patients who had markedly higher deficiency rates than male controls (67.0% versus 49.2%, P=0.0006) that increased with advancing radiological stage and were not confounded vitamin D-impacted comorbidities. Conclusions: vitamin D deficiency is a prevalent risk factor for severe COVID-19. Vitamin D supplementation might be an inexpensive and safe mitigation for the SARS-CoV-2 pandemic.

[Skybird]

https://www.researchsquare.com/article/rs-21211/v1

WHO declared SARS-Cov-2 a global pandemic. The aims of this paper are to assess if there is any association between mean levels of vitamin D in various countries and cases respectively mortality caused by COVID-19.
Methods: We have identified the mean levels of vitamin D for 20 Europeans Countries for which we have also got the data regarding the morbidity and mortality caused by COVID-19.
Results: The mean level of vitamin D (average 56mmol/L, STDEV 10.61) in each country was strongly associated with the number of cases/1M (mean 295.95, STDEV 298.73 p=0.004, respectively with the mortality/1M (mean 5.96, STDEV 15.13, p < 0.00001).
Discussion: Vitamin D levels are severely low in the aging population especially in Spain, Italy and Switzerland. This is also the most vulnerable group of population for COVID-19.
Conclusions: We believe, that we can advise Vitamin D supplementation to protect against SARS-CoV2 infection.

[Skybird]

https://www.ncbi.nlm.nih.gov/pmc/art...7Rv9v6yhDmT-4U

Molecular insights on nutrient-sensing systems allow a more integrative view of the reaction of the human body to dietary molecules. Vitamin D and its metabolites belong to a small set of dietary compounds that have direct effects on gene regulation. The analysis of vitamin D signaling via next generation sequencing technologies in in vitro cell culture models as well as in primary cells, such as PBMCs, has generated large amounts of data on the vitamin D-triggered epigenome and transcriptome in the respective cellular systems. Since the micronutrient connects cellular metabolism with immunity [94,95] (Figure 2C), nutrigenomics of vitamin D has a pleiotropic physiological and clinical impact. Personalized nutrition, such as tailored vitamin D supplementation, will contribute to the maintenance of wellbeing and the prevention of age- and lifestyle-related diseases, in particular those related to chronic inflammation.

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Guys, Vitamine D3 is cheap to have, and the conventional medical wisdom of your house doctor is maybe decades behind the status quo of science. On food, and supplements, most doctors tend to be extremely, extremely conservative, and I totally disagree with that. Manipulate probabilities in your favour: take it, together with K2 and Magnesium. It may change the game for you if you happen to get hit. Choose however wisely, espeically with Vitamine K2 studies from 2013, 2016 and 2018 show that the overwhelming majority of products are seriously underdosed, comparing to their printed claims on the box. Most such products lack 30%, 50%, 70% of the printed dose, confirmed in studies for the markets in India, New Zealand, USA, and Germany. Some even have no included K2 at all. The situation is not different with Vit-D supplements, even those for clinical use and high dose treatements via injections, only that these products can even be dosed higher than printed - even true for some products used in hospitals. That you get something from your doctor, unfortunately is no guarantee that it is a good product. My impression is that producers not so much want to make additional money by betraying, but that they simply are not in full control of the production processes. QA fails, probably mostly due to unwanted oxidation processes that get not properly compensated for. If you want to maximise your chance to get a good product, I recommend these steps:

- Make sure you buy from a company that indeed produces in your own Western country, not in Asia.

- The producer should have an own web shop stationed - with an existing company HQ - in your country.

- They should answer your email request for a laboratory report by an independent lab regarding the concentration of the claimed ingredients in the product. Make sure you get a link to or a copy of this analysis report/certification (it should even be renewed yearly) - not just an avertising text or a lab report regarding chemical or bacteriological contamination. The latter often is used all by themselves for advertising. Content anaylsis you have to explicitly ask for. If they cannot meet these criteria - avoid them. What they print on the boxes, is not the criterion you form your buying decision on. You want an independent lab certification.

As a rule of thumb, once again:


~50 I.E. Vit D3 per kilogram body weight. If you are "fatter", BMI above 25 or so, this can be risen to up to max. 80 I.E.s for very obese people. Vit-D gets stored in the fat cells, and the more of these the body has, the longer it takes and the more difficult it is to fill these all up - not before then Vit-D starts to flow in the blood stream as well, where you want it.
Take Vit-D3, not D2. D2 is vegan, D3 is from animals. Problem is our bodies almost not use D2, it gets transformed into D3, but at a ratio of 7:1 at best, probably even much worse (7 units of D2 are used to make 1 unit of D3). D2 is not used in the body directly. Serious products always are D3, never D2.

For filling up your reserves quickly , consider to take a single event dose of 50,000 IE, then two weeks long 10,000 every day, and then a maintenance dose of 3000-5000 I.E.
Myself, I took 20,000 daily for two weeks, 10,000 daily for another two weeks, and since then 5,000 per day.

Vit-K2 is a bit more complex, there are variations. To cut it short, avoid K1, your body cannot make use of it. Avoid so-called all-cis K2, only accept all-trans K2. Avoid K2 MK1 or K2 MK4 - only accept MK7. So the Vitamine K you want is named "all-trans K2 MK7". 200 micrograms per day. K2 can be more easily overdosed, avoid that. Mixes of any of the above you do not benefit from, but you waste money. all-trans K2 MK7 is all you need, want and pay for.

Magnesium: 250-350 mg per day, in that range. Leave some hours between taking K2 and Magnesium, if taken together the magnesium will neutralise much of the K2. They should be taken separately.