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Old 03-15-20, 05:56 AM   #1231
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Yesterday or the day before claims emerged that the university of Vienna should have run research finding that Ibuprofen could worsten Corona-19. This claim, basing on a pivate conbversation of the rporting perosn with soembody claiming to work at the university, seems t got picked upo by Fremnch offiocials, echpoing this warning. However. The French do not refer to the Vienna story, but an article in the Lancet some days ago, but an article that does to describe esotaboished, confirmed findings, but y hpyothesis so far cmlared only against a ver ylow case number.


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The [French] minister's recommendation is not based on the alleged research results from Vienna, but on an article published three days ago in the renowned specialist magazine "Lancet". Three doctors indicated that drugs that inhibit the cell receptor ACE could possibly worsen the course of Covid-19.

The idea: There are so-called ACE receptors on the cell surface, to which the ACE enzyme binds. It is precisely these receptors that the coronavirus uses to penetrate the cells. ACE inhibitors intercept the ACE enzyme, the ACE receptors remain free and the viruses can penetrate more easily. The cells may even increase the number of receptors when the enzyme is trapped. This would give the viruses even more opportunities to enter the cell.

According to an unconfirmed hypothesis, ibuprofen is said to have a similar effect. However, it has not yet been checked whether this is true. The "Lancet" article is explicitly formulated as a hypothesis. Because the number of patients involved is far too low for a hard scientific study: the researchers only look at the course of the disease in 32 Chinese patients who died in the intensive care unit in the past few weeks.

Ibuprofen also does not act as an ACE inhibitor, but influences other substances in the body: prostaglandins. These tissue hormones affect a number of organs, somewhat the circulatory system or the eye.

So the ibuprofen hypothesis is very shaky. It is not enough to draw a clear conclusion. It was not tested at the cell level whether ibuprofen - via whatever mechanism - leads to the fact that the virus can penetrate the cells more easily.
I woudl reocmmend to not take fever killers at all as long as the fever is not a threat in itself. Becasue high temperature is a wepaon by whcih the body tries to fight the attacker. Force the body to lower the raised temperature and you ban this weapon and bind it one hand on its back.

I rarely get a cold of flu these years, but if I see it coming, I try to artifically RAISE my temperature, until I sweat. It shortens the sickness' duration.

Corvid-19 is associated with low degrees of mild fever, in the mid and high 37°C range. Let it do its job. If you feel your breath runs short or a pain is appearing in your chest, respiratory system and lungs, then you are a "complication" and then you need to fight for your life - get contact with the emergency service immediately. pneumonia also means reduciton of oxygene supply fr your body and organs, - short breath signficantly weaken your body'S defences on all levels, lowering your chances. This weakenign turns into failing, and it is a progressive process. It is nothign you want to fool around with.

If you fele just symptoms of a mld flu, mild fever, dry cough and nothign more, self-isolate and self-quarantine - tell people to stay away and not enter you flat. But do not bother the ambulance people - they already have their hands full with more severe things. Call your national emergency number only if you are not a mild case. Also, you do not want to go into hospital easily these days, you risk of getting even more seriously infested there. Even by staff.

However, so that thsi also is clear, do nto avoid hpspital help at all cost. Where need is, call for help. Where you suffer just mildy from Cordiv-19, stay out of the way and stay in self-quarantine for two weeks. But where you feel you run short on breath, immediately call for help, because then your case is serious.


Everybody, stay away from others. No visits. No meetings. No social life. STAY by YOURSELF, and away fro toehrs as much as you can. this is the way we all need to fight this beatst - and can defeat it. STAY AWAY FROM each other, if you are not in the meedical business or work in essential services.


And thank those who are risking their own health and family and wellbeing in fighting against this and helping patients in hospitals. Thank them where you have the opportunity, and send them a friendly thougt every damn day as long as this battle lasts. Its war, and they are the ones at the front. You owe them. You are in no position to demand them. YOU OWE THEM. Their decision to stay in these jobs, deserve our utmost admiration, and where possible, practical support.


Where you still can, go donating blood. Here in Germany, blood donations have broken in to just one fifth of their former levels. Blood can be stored just 6 weeks. The shelves in the blood banks are almost empty. They desperately cry for help, the situation already is critical.






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Last edited by Skybird; 03-15-20 at 06:15 AM.
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Old 03-15-20, 06:17 AM   #1232
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DIY Ventilator?




I wonder if a cpap machine might be useful if you can't get on a ventilator?
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Old 03-15-20, 07:02 AM   #1233
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More and more reports come in in Germany that in regions already heavily affected, hospital staff, nurses, are as good as completely infected themselves already. Also, that in many houses staff does work without protective suits and masks.

This is worrying, because compared to others we still are int he openign stage of the match. We have the highest density of intensive care beds worldwide, we have one of the highest rates of machineries per bed worldwide, at we rank amongst the absolute top regarding hospital bed density in egneral. We have the beds, we have the ventilators and amhcines - but we are notoriously runnign low on nurses, already in peace times.

They now want to reactivate pensioneers.

The german problem no. 1 most likely will be that we run out of nurses.

Reminds me of the old Starfighter problem the Germans had: too many planes, too few maintenace crews. And so they started to drop down from the sky and did not stop.

I hear the british have opted for wanting to enforce her immunity by letting the infestation run. this is probaly the ost stupid thing they could dok sinc etheir health system is absolutely unfit for this. It will get overwhelmed by too high case numbers in too short time, and then more people will die than was necessary. I call it a deliberately murderous policy.

This will break Johnson's neck. I could even imagine that in the distant future he will go on trial for this.

Britian has a beds-per-1000 population ratio of just 2.4 or 2.5 (that is significantly less than Italy), and is desperately short on ventilators.

"They will fall like the flies".
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Old 03-15-20, 07:06 AM   #1234
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The health secretary has told Sky News that over-70s will be asked to self-isolate "in the coming weeks" to try to protect them from coronavirus - and it could potentially last for months.

https://news.sky.com/story/coronavir...onths-11957770
Useless dumbass, sack him now.

So how our my folks going to do their weekly shopping, keep their GP and Hospitals appointment let alone pop out to buy something that they need. Of course this will be the case up and down the land with over 70's.
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Old 03-15-20, 07:12 AM   #1235
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Originally Posted by Skybird View Post
If the German government lets this happen, it should get court-martialled, so to speak. Its in the vitla interest of germany and the world outside America to deny this move at any cost and even by use of force, and if needed the state should even take over this company.
"If the German government lets this happen" ?
So Trump has to buy stuff elsewhere because he can't do it himself after blocking research with his anti-science program three years ago. And now he wants to buy a german company and transfer it to the US, and next wants to have the patent on the vaccine, to make money with it.

Words fail me.
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Old 03-15-20, 07:13 AM   #1236
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Corvid-19 is associated with low degrees of mild fever, in the mid and high 37°C range. Let it do its job. If you feel your breath runs short or a pain is appearing in your chest, respiratory system and lungs, then you are a "complication" and then you need to fight for your life - get contact with the emergency service immediately. pneumonia also means reduciton of oxygene supply fr your body and organs, - short breath signficantly weaken your body'S defences on all levels, lowering your chances. This weakenign turns into failing, and it is a progressive process. It is nothign you want to fool around with.

If you fele just symptoms of a mld flu, mild fever, dry cough and nothign more, self-isolate and self-quarantine - tell people to stay away and not enter you flat. But do not bother the ambulance people - they already have their hands full with more severe things. Call your national emergency number only if you are not a mild case. Also, you do not want to go into hospital easily these days, you risk of getting even more seriously infested there. Even by staff.

However, so that thsi also is clear, do nto avoid hpspital help at all cost. Where need is, call for help. Where you suffer just mildy from Cordiv-19, stay out of the way and stay in self-quarantine for two weeks. But where you feel you run short on breath, immediately call for help, because then your case is serious.

I read an article today that said the rule with this virus as learned in China so far seems to be 80-15-5, i.e. from all people who get infected 80% have none or mild symptoms, 15% do have more severe ones and might need hospitalization at some point, and 5% will die. The main problem is that when that 15% is of a big amount of people because it is so infectious, the 5% raises because people that normally could be recovered won't any longer be in an overstressed health system. As more and more of that 80% of people get immune, the ratio of infection will decrease as there will be less people able to transmit it. The idea in Italy, Spain and such, even if acting criminally late and not enough in my opinion, is to flatten the curve so that even if most population get infected, which will happen anyway, the health system is not so much overstressed and you can save as many of that 15% as possible. In the UK, it seems that Johnson is embracing that idea completely and going for a "controlled" (LOL at the illusion of control) allowance of it spreading.

So no, this is not Walking Dead or the end of humankind by far, but still it's going to kill many people and wreck the economy and many concepts we took for granted. The elephant in the room is globalization and places like China with their wet markets being a nest for such sanitary emergencies. Once this all is over, the world should better start thinking seriously about capping once and for all much of the nonesense that has been going on like unlimited tourism everywhere, nearly uncontrolled acceptance of people and goods from countries that have no sanitary guarantees etc.

It isn't fun though sitting here taking chances at you or your loved ones being in that 15% or not ...
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Old 03-15-20, 07:29 AM   #1237
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Here's a crazy video I came across taken recently at a Costco in California. Must be at least 1,000 customers waiting in line.


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Old 03-15-20, 07:37 AM   #1238
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Originally Posted by Catfish View Post
"If the German government lets this happen" ?
So Trump has to buy stuff elsewhere because he can't do it himself after blocking research with his anti-science program three years ago. And now he wants to buy a german company and transfer it to the US, and next wants to have the patent on the vaccine, to make money with it.

Words fail me.
How are you even surprised? He wanted to buy Greenland, after all. There's a reason most of the planet is laughing at him, and openly so.
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Old 03-15-20, 08:05 AM   #1239
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Originally Posted by Catfish View Post
"If the German government lets this happen" ?
So Trump has to buy stuff elsewhere because he can't do it himself after blocking research with his anti-science program three years ago. And now he wants to buy a german company and transfer it to the US, and next wants to have the patent on the vaccine, to make money with it.

Words fail me.
My fear is that he wants to monopüolizte it for powerpoltical reasons. And of coruse toi distract from his own monumentla failure in all this. Lets face it, and I do not care whether I sound anti-Americna with this statement or not (it snot itended ot be, but some will see it as that): the samericna system has awfully, terribly,m monumentally failed until here.



The WHO has terribly, awfully, monumentally failed as well. Which confirms my deep mistrust for such huge supranational organisations. They lacked behind the going by many weeks from all beginning on, and still do so.



Best reactions I have seen so far, the quickest and sharpest shooting, came from Taiwan, Singapore, South Korea.



Until two days ago, the US had not done as many tests in the past months together as Korea does in a single day!! And even yesterday and today the rate is so hilarious that I would describe it as that they do not really test at all. Pure chaos. And a complete and total failure of the management at the very top. Which has worstend the situation in recent years by unexcusable budegt cuts for the CDC - demanded, authorized and signed by the great presidente! (tm) of the United States. And his sectarian church still sings his song!



For the US, this is not just a desaster like for anyone else. Its a disgrace. I mean this is not Sudan or Yemen or some god-forsaken bananan republic, but its the US! Its as if they got pearlharboured again, this time even with friendly assistance and handing over of maps and intel info by El Presidente himself.
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Old 03-15-20, 08:22 AM   #1240
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Old 03-15-20, 09:00 AM   #1241
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Quote:
Originally Posted by Skybird View Post
My fear is that he wants to monopüolizte it for powerpoltical reasons. And of coruse toi distract from his own monumentla failure in all this. Lets face it, and I do not care whether I sound anti-Americna with this statement or not (it snot itended ot be, but some will see it as that): the samericna system has awfully, terribly,m monumentally failed until here.



The WHO has terribly, awfully, monumentally failed as well. Which confirms my deep mistrust for such huge supranational organisations. They lacked behind the going by many weeks from all beginning on, and still do so.



Best reactions I have seen so far, the quickest and sharpest shooting, came from Taiwan, Singapore, South Korea.



Until two days ago, the US had not done as many tests in the past months together as Korea does in a single day!! And even yesterday and today the rate is so hilarious that I would describe it as that they do not really test at all. Pure chaos. And a complete and total failure of the management at the very top. Which has worstend the situation in recent years by unexcusable budegt cuts for the CDC - demanded, authorized and signed by the great presidente! (tm) of the United States. And his sectarian church still sings his song!



For the US, this is not just a desaster like for anyone else. Its a disgrace. I mean this is not Sudan or Yemen or some god-forsaken bananan republic, but its the US! Its as if they got pearlharboured again, this time even with friendly assistance and handing over of maps and intel info by El Presidente himself.
What else to expect from a businessman so bad he bankrupted several casinos? It's a disaster and a disgrace, but not a surprise.
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Old 03-15-20, 09:09 AM   #1242
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Supermarkets are urging shoppers not to buy more than they need amid concern over coronavirus-linked stockpiling.

In a joint letter, UK retailers have reminded customers to be considerate in their shopping, so that others are not left without much-needed items.

"There is enough for everyone if we all work together," it adds.

https://www.bbc.co.uk/news/business-51883440
I suspect they are wasting their time and breath.
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Old 03-15-20, 09:14 AM   #1243
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Originally Posted by Traveller View Post
Here's a crazy video I came across taken recently at a Costco in California. Must be at least 1,000 customers waiting in line.

Man, trying not to be judgmental here but wow. People are so ..... wow.

Last edited by Onkel Neal; 03-15-20 at 12:27 PM. Reason: off topic
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Old 03-15-20, 09:44 AM   #1244
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And then that moment back at home, when they unpack all their treausres and realise that they forgot that one precious little thing, that little box of sweeties they so desperately craved for, that one ingredient without which they cannot cook for their friends thta evening...


Or worst: if they realise they forgot the loo paper.
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Old 03-15-20, 10:01 AM   #1245
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Originally Posted by Rufus Shinra View Post
What else to expect from a businessman so bad he bankrupted several casinos? It's a disaster and a disgrace, but not a surprise.
Your job Rufus seems to be one that discredits our President at every opportunity given ... I now suspect you are being paid to do this by a group of people known as trolls

https://www.psychologytoday.com/us/b...hs-and-sadists

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Internet Trolls Are Narcissists, Psychopaths, and Sadists Trolls will lie, exaggerate, and offend to get a response.
The only reason that you upset me is that it is a waste of time to read your post.

Skybird at least makes good sense in his approach to helping us solve this Covid-19 problem even though he also dislikes our president to the point of calling hims silly names.

His advice is most welcome, but if you continue to upset me I will ignore you and hope others will stop interacting with you also.
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