Ok I'm new here, but Mods causing instability of game?

Hi guys,
I've posted a few times but not really introduced myself.

I'm Max, a serving owner of "Kissing Fish" and have been playing SH 4 and 5 for some time, however I have only started modding SH5 in the last few weeks.

I've gotten some great mods on and I'm really impressed with how thy improve the game. However, since installing open horizons 2.2, my game will run fine, then randomly CTD. Sometimes its after 5 mins, other times after 2 hours of game play (more irritating of the two).

My Mod list is as follows;

FX_Update_0_0_21_ByTheDarkWraith <<
MightyFine Crew Mod 1.2.1 Alt w beards
NewUIs_TDC_7_4_2_alt_officer_wounded_by_Torpedo <<
NewUIs_TDC_7_4_2_AltAdvSpeedGraphics_by_naights <<
NewUIs_TDC_7_4_2_ByTheDarkWraith <<
Dynamic Environment SH5 Basemod (realistic version) V2.1 <<
Dynamic Environment SH5 Waves (realistic version) V2.1
Dynamic Environmental SH5 Shallow Waters V2.1
OPEN HORIZONS II_full v2.2

There are in the order that they appear on JSGME, some are overwritten by others (indicated by << and end)

Does anyone with knowledge see some obvious mistake here?
I would gladly appreciate any help.

yours,

M