You can try removing the file from the game (save it somewhere, just in case) and see if this accomplishes what you are seeking. It may cause a game crash, it may cause an error message and the game will continue and it may work with no error message (my bet is one of the first two).
The other alternative is to change the file to be blank so that nothing shows up in game. You could do this several different ways. You could use Photoshop (along with the dds plugin available from nVidia at
http://developer.nvidia.com/object/p...s_plugins.html or you could search the forum for the other dds tools.
Or, you could try the mod I mentioned and see if the reduced size is sufficient to alleviate your problem.