I've got windows 7 on one computer, and windows 10 on another, and for both, I used CapnScurvy's thread
Windows10; Large Address Aware; SH4 Install as my base. He talks about Windows 10 and SH4, but it applies across all Windows from Vista 64-bit on. Others probably have their favorite way. Another choice is to use
NTCore's Utility, or even hex edit the executable yourself. If you want to run H.sie's patch, you could do that, but Be sure and
read up on it though. It isn't necessary for the 4 gig patch, but does have it on the menu. I'm not familiar with the Front_End.