Ratz on the no snake eyes... You're good to go on the install, and the card is not the issue. I would be more inclined to blame Windows 10. Do you have the last major update applied (creator??)? THEBERBSTER has a bit on that in his post
SH4 <> TUTORIALS <> HOW TO DO IT ... in the first link on that page there. Read through it, and see if you think it applies. I don't really, but then again, I don't have SH4 running on Win10.