This is the screen he is talking about.
I think it has to do with a corrupted gamesave and nothing with mods, or with the video card.
I have this problem also on long missions I play with many saves (no other ships near during saves).
At one stage the GUI side bars go completely white, as does the UZO. Reloading solves the sidebar problem but then the UZO overlay (binoculars) has vanished and you get the screen posted below. I am on the same version of TWoS as he is.
System: 2.33 dual core, Win10 home, Nvidia 720.
Entering base and starting a new mission generally solves it. Nothing to do with cfg files.
OLtzS Ashikaga