Well first thing is what your trying to build? Gaming rig? and if so how powerful. 1000 pounds should, I think, be plenty sufficient to build a good system.
As for where to start, start digging around sites that offer built computers of the kind your looking for, then see what components they are using (or poke around the threads here for builds). Then start researching components, like video cards, motherboards, cpus, etc. Look for reviews and customer feedback (like say newegg.com). Also ask questions here about parts your interested in. When you have narrowed your build down you could ask for comments on it from us on it as a whole.
That or just buy from Dell or the like. XPS is their gaming rigs (or Alienware but I don't like them as you pay through the nose for the name)
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