There is no right or wrong answer, it is really a question of personal taste. I tried RFB for a long time, and then TMO for a long time. In both cases, I wound up tweaking both to my personal taste. Currently using GFO+RSRDC, with some additional mods.
The problem you quickly run into are the inherent game/AI/design limitations that cannot be addressed by mods.
Every Supermod has strengths and weaknesses, best way is to try each and pick the one you like the most.
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