Shift+F1 also pauses the game (and brings up the help menus)
As to the people complaining about not being able to pause to set up attacks, it's not like Dangerous Waters or other more complicated games where setting up attacks is more detailed. It's literally selecting a few weapon behaviors (shallow, deep, search pattern), which you should have plenty of time to do as you're maneuvering to set up a shot. Then it's just Space > RClick.
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