Don’t know what to tell you mate...assuming you are not playing older saves?
All advice i can give you:
- re-install brand fresh SH4 up to date (V1.5)
- re-install JSGME application
- delete your Document/SH4 (it will be automatically re-created)
- install Large Adress Aware application linked to your SH4.exe
- make your SH4.exe not read only in properties (same for Document/SH4)
- check the right mods path by opening each one (must be always Mod name/Data)
- give your SH4 the high priority running each time you launch it
- prey... and finger crossed
Good luck