assuming you haven't knocked the case and unseated both drives from their connectors, if this is a laptop - it is probably a software issue.
You can try getting rid of the filters - that sometimes works
- Click Start, then Run, then enter REGEDIT to open the Registry Editor
- Navigate to the HKEY_LOCAL_MACHINE/SYSTEM/CurrentControlSet/Control/Class entry
- Under the Class entry, double click on {4D36E965-E325-11CE-BFC1-08002BE10318}
- In the right-hand pane, click ONCE to select the UpperFilters entry
- Make sure the UpperFilters entry is highlighted, press Delete, then Yes.
- In the right-hand pane, click ONCE to select the LowerFilters entry
- Make sure the LowerFilters entry is highlighted, press Delete, then Yes.
- Close the Registry Editor by clicking File, Exit.