As said, I have had no issues (there was one but it was due to lack-luster nvidia drivers got my old 8800gts 640)
Been solely running vista ultimate x64 for ages here with no problems (found a fix for old nvidia card but now have a ati 4870 and latest 8.9 drivers rock in sh4)
Gotta get sleep badly here, But have a squint over for a post i did about nvidia driver fix on the silent hunter 4 wolves of the pacific forum (top forum)
Get a driver that i uploaded (should still be up in cyberspace i think)
That may cure your ctd (just saw you have a GT card)
pps: slap another 2gig of ram in ya rig if you can, You won't regret it