Just some tips: there are a bunch of things to avoid. Here are a few that I can think of...
1) Don't save games anywhere near other objects (ships & aircraft) or land. A lot of people experience ctd's when they do this.
2) Don't save while submerged. Same reason as #1.
3) Don't use the crew configuration screen to move crew around. Do it manually. See the GWX manual for details about that one. Although I've never had a crash when I've used it a lot of people have.
4) Avoid using high TC (64x +) near large convoys. The game starts to really lag & may crash on you.
Hope that this is useful to you.
