Thanks Banjo
It's all working again. I didn't do anything obvious, although I did reinstall TMO, and then downloaded Alacrity (thanks for the tip) out of interest (it frees up a surprising amount of memory!).
However, I wasn't running Alacrity this time, but it still runs nice and smooth again (maybe Alacrity give Vista a kick up the backside when I ran it though). I'm also running it on the highest settings in the graphics config too, which is nice!
I'm putting it down to Vista being naff :-)
Cheers
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