Aint gonna happen
1. The RDS-220 was only produced once with several airframes of which one is on display. I doubt that the Russians have the machining equipment to make another one. Not that they would want to because...
2. By now the Russians have learned what we knew for years. Several smaller nukes can do more damage than one big one.
3. The current variants of the TU-95 are probably unable to carry the RDS-220 even if it were built.
The RDS-220 was simply a propaganda weapon.
We are all lucky that there was a delay in machining the uranium tamper lenses so the Russians switched to lead or there would have been considerable radioactive fallout. Redacted due to lack of citation
Useless trivia question
While a shortage of Uranium may have saved the world, what shortage did the RDS-220 cause in the Soviet Union?