Overandout,
To determine target course, use your nav map and zoom in as much as possible to see your targets. Mark the middle of your target. Wait a few minutes and mark the new position. The more often you do this, the more accurate your plot will be. When you've got a few marks, draw a line connecting them. Now...set your sub's course to intersect their course at a right angle. And, as joegrundman pointed out, make sure to get an accurate speed estimate. Hope this helps out a little!
Good luck and good hunting,
Howler