I just installed it on my home built AMD / ASUS system. After it installed it wouldn't boot, not even into safe mode. Called MS and they said a level two tech would call me on Wednesday.
I Googled around (thank God for Google) and found a thread where others with AMDs were having the same problem. To get it to boot they suggested a USB flashdrive on a usb port. Tried it and it booted right up - I then proceeded to unistall SP3.
When will I ever learn not to patch something right away from MS.