I'm so sorry to hear the bad news concering your close mate and compaion Niki. 
Been a dog lover all my life and we have always had dogs in the family. I have two back home in Australia, a female Dalmation named Ali and an Aussie Blue Heeler cattle dog named zack who run around a huge property.
Only you with the aid of the vets advice can make the call as to when your buddies quality of life has past that point when it is time for him to go to that better place called doggy paradise. It's darn obvious how much you love him and have looked after him so your judgement will be right. Stay strong. 
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"In a Christian context, sexuality is traditionally seen as a consequence of the Fall, but for Muslims, it is an anticipation of paradise. So I can say, I think, that I was validly converted to Islam by a teenage French Jewish nudist." Sheikh Abdul-Hakim Murad (Timothy Winter)
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