Are you saving them as a .dds file, or another format while working on them?
tga is a better "working" format and then do the final export to dds The other thing that affecst this is the number of mipmap levels created during the save. The fewer mipmap levels, the less clear it looks. I think this is selectable with the nvidia plugin.
The other problem you may be having is the game resizing the texture for your screen resolution.
You can try a higher res texture, but you might have to remap it to get the references correct.
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"There are only two types of ships- submarines...... and targets" Unknown
"you wouldn't catch me on a ship that deliberately sinks itself"- comment to me from a surface sailor. 
System:
AMD 6300 3.5 GHz | 32GB DDR3 | SATA 300 320GB HD, SATA III 1TB HD, SATA III 1.TB HD | ASUS Sonar DS sound card
NVIDIA 1660 Super OC | Windows 10
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