I just started a new career in GWX2, and went with starting in the Med this time (albeit in a VIIC, not a B). On first patrol, we did bag a Dido and a Southampton, and we are now out on our 2nd patrol. So 10K tons for the Southampton is the biggest vessel thus far this career.
In my history of playing SHIII, I once came across the Nelson, Rodney and, err, the NelsonII/RodneyII. Yup, 3 Nelson class all in a row, with cruiser and DD escorts. I only managed to sink the lead two
(was in a IXB). I also remember the first time I ever even saw a big liner - coming out of the Med. - I put 4 torps into it since I had no idea how much it took to sink something over 50K tons. It blowed up real goood
P.S. this was stock SHIII, within a few weeks of it's initial release, so I did not have any mods at all.