IMHO, best to take the targets most likely to result in success. Your efforts will be appreciated even if you do not sink a high profile target like the Yamato.
Then the
in me takes over and says fortune favors the brave so get in there and take out so major targets that would really demoralize the rest of the TF.
(It is a pity that such things are not accounted for in the AI, Flagship sunk = 15% drop in morale & poor performance from all units within visual range)