The Nelson.
Got the sucker while roaming off the portuguese coast. He was travelling in a task force, but luckily they were going slow, the weather was crappy (overcast) and I caught them around midnight.
First I fired two eels, both hit. The Nelson stopped and leaned to the starboard side. The escorts didn't really care and disappeared in the night, leaving me all alone with the dying giant. I made another run and hit him twice in the port side.
Having all the time in the world, I surfaced and watched him disappear beneath the waves.