Well, I just recently got Silent Hunter 4, and also, I built a new PC. SH4 runs beautifully on max settings and 1280x1024x75 resolution. Theres only a couple issues I notice and it's either the drivers or the games compatibility with my video card in general. I notice when looking out at ships or land, it gets really stuttery, but, it's not frame lag at all. I loaded up fraps (note: I have vertical sync ON), and to my surprise, even when its stuttering, I'm gettin' 60-65FPS. My framerates max out at 75 (because of the vertical sync, with it off I can get higher but I notice a lot of tearing) when inside the sub constant. This also happens when looking right at my sub from external view, some stuttering yet my frames are still 60-65FPS or higher. I also notice around my sub and other ships, white lines around the edges when looking at the parts under water, basically like a white "tracing" around the waterline of any ship.
It must be driver or game support, because my system obviously has no problems running it.
My Rig:
Thermaltake Armor Full-Tower ATX (plenty of cooling, 2 120mm fans, 2 90mm fans)
Intel Core 2 Duo Conroe E6600 Processor @2.4GHz (combined 4.8GHz) 4MB L2 Cache (combined 8MB) (Dual Core

)
eVGA 122-CK-NF63-TR Special Edition 680i SLI Motherboard
2GB (2x1GB) Patriot eXtreme DDR2 800 (PC2 6400) RAM
XFX GeForce 8800GTS 320mb 320-bit Video CArd (560 core clock/1700 memory clock)
Thermaltake Toughpower 700W Power Supply
Western Digital Caviar 250GB SATA Hard Drive 3.0Gb/s @7200.10RPM
Samsung SATA DVD+R Burner
By the way, all clock speeds are stock, so no artifacting or overheating is taking place.