Yes, mine can most definately run SH4. Runs everything else too. 
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Specs
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AMD X2 6000+
Asus M2N32 SLi N590
4GB PC6400 (DDR2 800)
Dual 8800GTXs in SLi
Creative X-Fi Fatal1ty
150GB 10K Raptor w/500GB Backup
Antec TX1050B Case w/850W Coolmax PSU
Windows Vista 32/64 Dual Boot
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