The most memorable moment for me was back when I was using GW1.1a and I was attacking this convoy. I was right in the middle of them, trying to keep track of all the ships, especially the warships of course. I was at periscope depth and had forgot to check my rear for a bit. I was trying to get into position to fire my forward eels at a target and had neglected to check my rear for a while. I fired off my shots and then swung my periscope around 180° to see that a DD was less than 500m away coming straight at me at high speed. Luckily, she was directly behind me. I hit crash dive and fired my rear torp, just hoping to get the warship to change course for a bit and whammo, about 15 seconds later, the DD went down in flames.
I thought that was pretty exciting.