People in England with a positive lateral flow test but no Covid symptoms will no longer have to take a PCR from 11 January.
This will be reviewed when the proportion of people with the virus in England drops below 1% for a sustained period of time, the UKHSA says.
And the government is expected to stop asking for pre-departure Covid tests for UK arrivals.
Boris Johnson will face MPs at 15:00 GMT in the first Prime Minister's Questions of 2022
At a news conference on Tuesday, he said he hoped the country could "ride out" the Omicron wave.
Sir Keir Starmer will miss PMQs as he has tested positive for Covid
In Scotland, Nicola Sturgeon reduces self-isolation for Covid cases from 10 days to seven.
And fully-vaccinated close contacts of cases in Scotland no longer need to isolate for ten days.
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