Last post, does not... take into account for needing jsgme dropped into the copy/pasted copy folder... nor, needing to have a copy of MultiSH4 in there, either. Both of which are strongly required... jsgme for ease of de-activating any mods you use, thereby keeping the copy, as pristine as possible.
MultiSH4 for making a separate save games folder, divorcing it from trying to attempt to save to the pristine copies save folder. (That will be made, when you run the pristine copy, in order to finalize it doing what is needed to, for it to play... (see, installing Microsoft's redistributable & the dx files & such the game needs...

) after initially installing SH4

) You do NOT want your copy sending game save info to the pristine 's save folder... at all. So, a definite must have.
Or, before doing any modding, of going into the "properties" section, for the copies SH4.exe to do what's needed there, either.
Which is covered extensively on the site... as is any tweaking that needs to be on the High DPI for it.
Gonna stop here, before I turn this into a novella...
As mentioned... I hope this info helps...