Talks on restrictions in Greater Manchester have ended without agreement and additional curbs are now expected to be imposed.
PM is to hold news conference at 17:00 BST with NHS England's Stephen Powis and medical adviser Prof Jonathan Van-Tam.
Before that, Greater Manchester mayor Andy Burnham is giving his own televised statement at a news conference in Manchester.
There have been 10 days of talks over moving Greater Manchester to tier three restrictions - a move that affects 2.8m people.
It is estimated that the tier three measures will mean that 1,809 pus will have to close their doors in the Greater Manchester region.
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Wise men speak because they have something to say; Fools because they have to say something.
Oh my God, not again!!
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