I've tried several ways Jeff, with command line stuff with a batch file, and it does not like it, though they say you can in the Help file under "Command Line Arguments". But if I try to pass a path to the file with its name, I get a Windows error message of "Windows cannot find 010 Editor.exe (command line)". I can start it from the command line fine, but not with a file path. You can start the program and -import a script etc., but not a regular file with a path. I wonder if adding a folder to the Options for 010, and having the "targets" there would then allow it to find the target file without a path? But that sort of defeats the "Search" that you've done... Maybe add a "Copy" to that folder to the script ? I'll keep noodling, because 010's command line interface is different from most other apps...
Wait... I bet you have to tell 010 it's a binary file if doing a dat...