Big news to hear. Like others have said, it's a big move for anyone. The United States boasts any kind of climate and ecosystem you can name. Almost everyone is descended from immigrants. There is tremendous differences in culture dependent on geographical location and where immigrants from certain countries settled.
Everyone thinks their area is the best to live in, but the truth is, every area has it's own advantages and disadvantages. You can choose to live in a big city, a small city, in the middle of nowhere, or someplace in between. Often, you can find a small, seemingly isolated town, just a short distance from a population center.
When you make your move, I like to think you will be made to feel welcome.
Best of luck when you do move.
