I haven't played for ages and, as I'm on a new PC I treated myself to for my birthday, I've not had Silent Hunter installed before on this machine.
Using the guidelines in this thread -
http://www.subsim.com/radioroom/showthread.php?t=212323 I've got the game installed and running at patch level 1.4b.
One issue I did have on first start up was an error "Can not initialize 3D " After trying a couple of recommended fixes that didn't work I let Win 10 diagnose the problem - it says run in in WinXP SP3 compatability, and that worked!
So I've got the game working, I just need to add a few more patches and mods from the community here and I'll be off!