Hi RD
I am running Windows 10 without a compatibility mode.
28" Asus monitor 1920 x 1080 60Hz in its native resolution.
GPU Geforce GTX770 4gb
SH4 Game graphic settings 1920 x 1080 60Hz
You need to make sure of the following settings.
Set the SH4 games graphic setting to match your monitor's resolution and hertz rate.
Peter