Whichever app you start first is the one that
has to run as administrator. So if you start SH5 via the SH5 icon (assuming Uplay isn't running already), SH5 will then start Uplay and spawn OSI.exe as administrator. If you start via Uplay, then it'll run the subsequent items as administrator. The same follows for if you start SH5 via KSD Commander as administrator, again provided something isn't already running.