I had the great opportunity to work from home for almost 2 years in a row. During that time I ran a 1x patrol over a whole summer, minimum of 8 - 10 hours a day of realtime game play, often sleeping near the computer with the volume loud enough to wake me if an announcement was made.
It really was an incredible experience and actually the sea sounds took the edge off the workday. lol.
What I found most incredible about it was the excitement at seeing ANYTHING.

Even when coming across neutral ships, I'd go through all of the motions of tracking and aggressing them without actually firing any torpedoes because the first thing I realized was that you can get really rusty and easily fail when it really counts. You end up keeping good notes, and even making up imaginary contacts to prosecute. I did have another machine but it was dedicated to paying the bills.
And if you think torpedo duds are frustrating now, try the frustration when you've spent several hours of tracking a target, after spending several days with nothing happening, and you fire and nothing goes boom.
There's a serious sense of satisfaction after completing a 1x patrol as GoldenRivet expressed. A serious sense of accomplishment. Because of that patrol, I have a really hard time playing with TC enabled now so I restrict the use of it highly.
In my opinion, everyone should try it at least once.