Nope, no conflicts with GWX. The problem is likely memory, as MFM is huge.
First, what are your specs? If you only have 4 gigs of RAM or less, it won't run. If you have more than that then you still need the 4-gig patch, which allows the game to use a full 4 gigs.
The best way to get that, and a lot more, is BL!TZKR!EG's Front End patch.
http://www.subsim.com/radioroom/down...o=file&id=4441