Actually any environmental mod added to TMO will definitely impact gameplay in some way not intended by Ducimus. If you don't care about really playing TMO then no problem. But if you want to play the game as tuned by Ducimus, actually playing TMO, then be very conservative about adding mods.
The one thing that pushed Ducimus to quit modding was people making bizarre recipes of mod soup, often over a dozen mods long, and then complaining to him about how TMO works. If you have layered mods on top of TMO you aren't playing TMO.
Only exceptions are skins, sounds and missions.
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