A Warm Welcome To The Subsim Community > darthpeace 
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My mod list
TMOwTw 2.50
wTw 2.50 Max Optics with Crosshair
Webster's Eliminate Floating Plankton
Eye Patch for TMO v1.7
Bigger Better Protractors
Convoy Routes TMO+RSRD
Pacific Sound Mod
Stop The Shouting
wTw 2.50 Stock Sub Underwater Marker
Yes you should be okay to enable in mid patrol as these are sound mods.
If you are using both of the sound mods then install them in this order.
Peter