What merc said. If you play your cards right, use your torpedoes wisely, and GTFO after firing, your chances are good. I've pulled off an attack on the Manila invasion force in an S-18. Took one hell of a beating, but made it back to port more or less intact...

You might want to have the cook make your crew one big meal before you set up your final attack. It'll make the potential depth charging not so bad!