OK,
I'll assume you have the dvd or non-steam version and it's patched (1.2 or 1.02 whatever it is)
So games in and patched
Get a known working vidcard driver (sometimes the latest is not always the best/most stable
)
Go google for something like cccleaner and display driver uninstaller
Get latest free version of ccc and ddu is free always
Run ccc to check for malware etc
Run ddu from windows, it will auto reboot to safemode (it will prompt for this)
Remove all traces of your vid driver
Follow prompts if asked and install fresh driver
Before the above check to see what MS visual C ++ you have (post back asap)
And one more thing, check your anti-virus/firewall settings, some like norton cause sh5 to not run, you have to set it to allow etc (don't ask me i hate norton and alike, always seemed like bloatware to me)
Most cases of that error are due to vidcard driver problems/malware (never had this myself) or ram going south (extremely rare)
Food for Thought
EDIT : best add, it's either one/some of the above or something you're doing, it's not the patcher
Don't dl the tool, but makes good reading doubleya doubleya doubleya 0xc0000005.com/