Hello Harcor,
Did you try playing the "Plain Vanilla" game; with no modifications whatsoever?
Adjust your graphic settings: shadows, anti aliasing, etc., hi or low?
If your performance is good without mods enabled you can begin to add just a few; one at a time, to test the performance of your computer. Add mods until you have that unexceptable slowdown. Then you must decide which mods are the most important to you.