I too use an Nvidia card, GTX 560 w/latest driver. I have AA set at 16xQ CSAA w/no problems. A good starting point is usually with the default settings, then make changes one at a time, load SH3 after each change to see what difference it might have made. I also googled most settings in the Nvidia Control Panel so I understand better what it is and how to adjust it for best appearance, vis-a-vis my computer hardware/specs/os.