By following vdr1981 advice I have reduced the CTD to zero. I now have 20 hours of playtime without any CTD. I have destroy ships with topedoes and with cannon without CTD. No CTD by using silentotto. No CTD at Kiel, Everything works without probem

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I use the following list of mods;
Accurate German Flags
Grossdeutscher Rundfunk
SteelViking's Interior Mod V1.2
SteelViking's Interior Mod V1.2.1 Patch
Conus' Medals
DynEnv v2.9 - 1. Main Mod
DynEnv v2.9 - 5.c Ambient Settings - Darker Nights-No Murky Waters
DynEnv v2.9 - 3.b Enhanced Visibility (high)
DynEnv v2.9 - 4.a Camera Filters - Realistic Colors
DynEnv v2.9 - 2. Main Mod Low Resolution Patch
sobers base sky mechanics V1
SH5_7A_Conning_Fix
MightyFine Crew Mod 1.2.1 Alt faces
MCCD_1.04_MFCM_1.2.1_compatible
Equipment_Upgrades_Fix_v1_4_byTheBeast
Equip_Upgrades_Fix_1_4_Patch_1_AFFOE_151
#Equipment_Upgrades_Fix_v1_4_Patch_1_HotFix
EUF_UBoat_FX_v0_0_3_ byTheBeast
FX_Update_0_0_22_ByTheDarkWraith
FX_Update_0_0_22_Torpedoes (modified for torpedoes failure patches)
FXU_0_0_22_Ship zon Files
Bullet_spark_test
NewUIs_TDC_7_5_0_ByTheDarkWraith
NewUIs_TDC_7_5_0_Real_Navigation
NewUIs_TDC_7_5_0_New_radio_messages_German
IRAI_0_0_39_ByTheDarkWraith
IRAI_0_0_39_ByTheDarkWraith_Patch_1
AI_sub_crew_1_0_2_TheDarkWraith
HydrophoneFollowNearestContactFix_For_NewUIs_TDC_7 _1_0_To_7_5_0
R.E.M_by_Xrundel_TheBeast_1.2
Cerberus62 Corrected Depth Charge Projector 1.0
Reworked Morale and Abilities v.1.1_modified
sobers green crew training V4 SH5
OPEN HORIZONS II v2.3
OPEN HORIZONS II v2.3 patch1 beta
AAguns_12_20_40mm
Rocket_3InchGB_&_5InchUS
Targor's SH5 Wooden Lifeboats ver. 0.4
Church's Compass Dials Mod v2.2 - Option Two
Kriegsmarine Career Insignia CrystalClear Extra
EQuaTool 01.01 by AvM - Medium Faber-Castell Style
Large Optics for TDW UI
Large Optics for TDW UI 16 by 9
R.S.D. - Reworked Submarine Damage v5.5 by vdr1981
R.S.D. v5.5 - OHII v2.3 Compatibility Patch
R.S.D. & R.E.M. - GHG Hydrophone add-on (normal)
Dynamic Environment SH5 Sounds V2.1
Moon_light_mod
sobers better terrain v4 SH5
Small_trees_SH5_V1
sobers more trees SH5
Water reflections intensity varied by available sunlight by TheDarkWraith
Shadow Improvement ModLR
These files, Shells_Rck.dat, Shells_Rck.dsd, Shells_Rck. sim and Shells_Rck.zon, is not included in OPEN HORIZONS II v2.3.
TheDarkWraith_DC_Water_Disturbance is not in my my list because it can provide CTD.