I've playing SH4 on my MacBook Pro, running osx 10.7.5 for the past year.
See this thread for some advice,
http://www.subsim.com/radioroom/showthread.php?t=201546.
I use Wineskin wrappers to run SH4 1.5 as well as JSGME to apply MODs. Read the post I reference as it tells you how to do it. Make sure the version of Wineskin and the engines you used are for 10.9, . The game runs fine with no additional Winetricks. When you start the wrapper, you simply install Sh4 as if you were using Windows. It's been over a year since I created my wrappers so I'm a bit rusty on details. I found the game runs better than when I used Bootcamp with Win 7.