I had the same issue.
I fixed it, by reinstalling SH5, and using
Sjizzle's snapshot for TDW's Generic Patcher (link at the bottom of the 1st post).
Make sure you first patch the game to v1.2....only then use the Generic Patcher.
Then install mods.
Also, I made sure that the folder-structure was correct for each mod, before enabling it in JSGME.
Read more
here.