[Redmane]

You won't have any problem crop up by installing JSGME at any point. The problem will arise if you install it incorrectly. Obviously any changes you make by moding the game won't be good for any current career you may have going. Once you've installed the mods you want to run, start a new career. Some mods can be installed and work successfully when you are in your home port. Others require a whole new career to be started after they are enabled.

With respect to installation of JSGME, it must appear in the root directory of the game. in my Win7 installation this is: Program Files (x86)/Ubisoft/Silent Hunter 4 Wolves of the Pacific. The easiest way to accomplish this is to place the installer for JSGME into that folder and run it. That way all you have to do is confirm that location as the one where you want the program to go when you run the installation. Once that is done, run JSGME. It will create the mods folder in the same folder as it is installed in. Then all you will have to do is place the mods into the mods folder and run JSGME to enable them. Hope this answers your question.