That could be caused by all kinds of things, maybe it´s a sound card related problem, maybe a graphics card problem or maybe something completely different. Some things you could try:
Try some other games, if they show a similar behaviour you know that it´s a general problem with your system.
Check you system for viruses and spyware (with Spybot and AdAware).
Move all gramophone files to another location to see if that is maybe the problem. They are in data\sound\gramophone.
Disable the hardware sound acceleration (Start/Run/dxdiag, Sound tab).
Install the latest soundcard driver, if that doesn´t help install an older version.
Try the same with the graphics card driver.
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