Personally I dont have much patience, so some times I just throw some new mods in and well it happens that there is a ctd on first start, then I move around the mods I just installed. If it doesnt help it have happend that I just take out all my mods and throw them in again in a order that looks good to me and try to play, worked last time I fixed a CTD.
My way is not very good and can create problems but I dont have any patience so what ever floats your boat so to say
