Im having the same problem. After starting a new mission after finishing coastal waters (in OHII v1.7) I find there is no crew on the bridge and the watch crew are stood around downstairs with thier arms out like loonies...
If I click on D. Epp to ask him to man the flak guns I get a CTD.
Normal fixing behaviour like diving or going to periscope depth then surfacing has not worked either! I started from the autosave entering port aswell but that didnt fix it. I have a feeling that when I went into port I had a problem with my mod soup with Mighty Fine Crew mod being overridden by something (should'nt be DBSM music or speech I don't think but thats what JSGME said) but as I can't find a fix yet it may have to be a new career. Here's a screenshot of what the crew are doing when they're not obeying orders to go topside...